Scientists Discover THC-Free Cannabis Compound That Could End Chronic Pain Without Opioids

 



A breakthrough study suggests that cannabis-derived compounds, known as terpenes, may provide a new solution for chronic pain relief, potentially reducing reliance on opioids.

Conducted by researchers at the University of Arizona Health Sciences, the research focuses on terpenes from the Cannabis sativa plant and their ability to alleviate pain without the psychoactive effects of THC.

Terpenes: A Promising New Approach to Pain Relief

Cannabis terpenes have long been recognized for their distinctive aromas and flavors, but recent research is highlighting their potential therapeutic properties.

According to a study published in Pharmacological Reports, researchers tested four key terpenes found in moderate to high levels in cannabis: geraniol, linalool, beta-caryophyllene, and alpha-humulene.

These compounds were tested in mouse models of post-surgical and fibromyalgia pain, showing significant pain relief with geraniol standing out as the most effective.

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Marijuana Users Have Triple the Odds for Leg Artery Disease, Study Suggests

 



MONDAY, May 15, 2023 (HealthDay News) -- Smoking cigarettes has long been linked to peripheral artery disease (PAD), a condition where the buildup of plaque narrows arteries and limits blood flow to the legs or arms.

Now, a new study suggests that marijuana may have a similar impact, after finding that users had three times the risk of developing PAD.

Although the study is preliminary and doesn’t determine whether the impact is all from smoking weed or other popular methods of using the drug, such as eating cannabis-infused gummies, it may be a red flag for users and could be something their doctors should ask about to gauge risk factors for their patients.

“Marijuana users should seek early evaluation by a health care professional if they have symptoms such as leg pain while walking, slower/no hair growth and coldness in the leg as there seems to be an increased risk for developing PAD in this patient population,” said study authors Dr. Hirva Vyas from Hackensack University Medical Center in New Jersey and Dr. Harsh Jain, a resident with the Montefiore Health System in New York City.


Read More Marijuana Users Have Triple the Odds for Leg Artery Disease, Study Suggests